Centromeric refers to the region of a chromosome where the two sister chromatids are held together during cell division. Synonyms for this term include centromere, kinetochore, and spindle attachment point. The centromere is a crucial structure for the proper segregation of chromosomes during mitosis and meiosis. Without a functional centromere, cells cannot divide properly, leading to genetic disorders such as Down syndrome or Turner syndrome. There are also various medical conditions associated with centromeric instability, where the centromere's structure is abnormal or unstable, leading to chromosomal instability and cell division defects. In summary, centromeric and its synonyms play a crucial role in maintaining the integrity of our genetic material during cell division.