Disaccustom is a word used to describe the process of becoming unaccustomed or unfamiliar with something. Synonyms for this word might include words like "unlearn," "unfamiliarize," "wean," "detach," or "detrain." Other synonyms could include words like "acclimate," "habituate," or "orient." Each of these words describes a process of becoming more accustomed to a particular situation or context, whether that involves learning new skills, adapting to a new environment or culture, or simply becoming more comfortable with change. Whatever the case may be, there are plenty of synonyms for disaccustom that can help convey the process of becoming less familiar with something.