Twattle is a word that has a negative connotation and is often used to describe someone who talks excessively about unimportant things. To avoid using the word, some synonyms that can be used include prattle, blather, ramble, chatter, blabber, gab, yammer, and jabber. These words all convey the idea of talking too much without saying anything of value. Another synonym that can be used is gossip, which refers to spreading rumors or talking about other people's lives without their permission. It's important to use these words carefully and respectfully, as discussing trivial matters can be fun and therapeutic in small doses.