Acquired immunodeficiency syndromes (AIDS) is a medical condition that causes a weakened immune system, making individuals more vulnerable to infections. Some synonyms for AIDS include acquired immune deficiency syndrome, immunodeficiency syndrome, and HIV/AIDS. HIV (human immunodeficiency virus) is the virus that causes AIDS, and therefore, the terms HIV and AIDS are often used interchangeably in many contexts. Other related terms include retroviral disease and autoimmune deficiency syndrome. It is essential to understand these synonyms to improve communication between healthcare providers, researchers, and individuals affected by HIV/AIDS, as well as to raise awareness of the impact of the disease on individuals and communities worldwide.