Synonyms for Against the grain:

• adj.

  •unwilling (adjective)
  • evasive,
  • unwishful,
  • wayward,
  • uncheerful,
  • compelled,
  • forced,
  • indocile,
  • disinclined,
  • unready,
  • unenthusiastic,
  • uncooperative,
  • shrinking,
  • Demurring,
  • reluctant,
  • unaccommodating,
  • Against,
  • loath,
  • slack,
  • uneager,
  • malcontent,
  • laggard,
  • indisposed,
  • afraid,
  • involuntary,
  • resistant,
  • disobliging,
  • grudging,
  • refractory,
  • remiss,
  • uninclined,
  • recalcitrant,
  • hesitating,
  • unobliging,
  • backward,
  • begrudging,
  • shy,
  • slow.

• Other synonyms:

  •
  • opposed.

Antonyms for Against the grain:

• adj.

  • opposed/opposing
    Aiding, compatible, helping, similar, Assisting.
  • unwilling
    ready, eager, enthusiastic, prepared, willing.