Aortopulmonary Septal Defect (APSD) is a congenital heart defect characterized by a hole in the septum between the aorta and the pulmonary artery. This condition is rare and can cause a variety of symptoms like difficulty breathing, cyanosis, and heart failure. Although the term APSD is widely used, there are alternative names for this defect, such as Aortopulmonary Window, Aorta-Pulmonary Fenestration, or Aorta-Pulmonary Communication. These synonyms are often used interchangeably and denote the same condition, allowing doctors and healthcare professionals to communicate effectively and offer proper diagnosis and treatment options for patients with this defect.