Bolixes is a colloquial term used mainly in Ireland and the UK. It means to mess up or confuse a situation or person. There are a variety of synonyms that can be used to express the same idea. These include words like bungle, muddle, flummox, perplex, mystify, befuddle, confound, and bewildered. Each of these words carries the same sense of causing confusion or complicating a situation. It is important to use synonyms effectively to convey the right meaning in communication. So, next time when you hear the word bolixes, you can use any of these synonyms to replace it.