Brompton's mixture is a well-known medical formula that contains a mix of opioid pain relievers and sedatives. However, due to the recent opioid epidemic in the United States, physicians have been looking for alternative medications that can provide similar relief without the risk of addiction. Some synonyms for Brompton's mixture include a combination of non-opioid pain relievers such as acetaminophen and ibuprofen, antidepressants like duloxetine or venlafaxine, or anticonvulsant medications such as gabapentin or pregabalin. Other options include non-medical approaches like physical therapy or mindfulness meditation, which can help reduce pain and stress without the use of prescription drugs. Consult with a healthcare provider to determine which option is best for your specific needs.