The phrase "come to an end" implies that something is finishing or concluding. In contrast, the opposite of this could be "beginning anew" or "starting afresh". Other antonyms for this phrase could be words or phrases that imply continuation, such as "endless", "continuing", "never-ending", or "eternal". These antonyms all suggest that the end of something is not in sight and that there is still a ways to go. Alternatively, antonyms could be variations of "not finished", "ongoing", or "incomplete". These all suggest that something has not yet come to a conclusion and is still in progress or has yet to be finished.