Copa-like RNA is a term used to describe a class of non-coding RNA molecules that are structurally similar to the Copa protein in eukaryotic cells. Copa-like RNAs are involved in a variety of cellular processes, including RNA interference, chromatin modification, and the regulation of gene expression. Synonyms for copa-like RNA include small interfering RNA, microRNA, long non-coding RNA, and piwi-interacting RNA. These different types of RNA molecules share similar properties with copa-like RNA and are used by cells to regulate gene expression at the post-transcriptional level. Understanding the functions and mechanisms of copa-like RNA and its synonyms can provide valuable insights into the molecular basis of gene regulation and disease.