The antonyms for the word "de-populated" are numerous, as there are so many words that describe the opposite of it. Some of the most common antonyms include words like populated, filled, occupied, packed, teeming, and thriving. All these words indicate that the place is well-inhabited and has a considerable amount of population. Other antonyms can be bustling, lively, active, and flourishing, which indicate that the place is bustling with activity and full of energy. These antonyms come in handy when describing places that are full of life and activity, and they help bring a better understanding of how a particular area looks like.