Depurated is an uncommon word that refers to the process of purifying or cleansing, often used in the context of medical treatments. Its antonyms are words that signify the opposite of purification or cleansing, and they include contaminating, polluting, defiling, tainting, infecting, and sullying. These words denote the action or result of introducing impurities or harmful elements, which can be damaging to the environment, people, or objects. Since depurated is not a commonly used word, its antonyms are more frequently encountered in everyday language, where they often carry a negative connotation. For example, pollution is a major concern in many cities, as it can have profound effects on public health and the environment.