Depurgating means to remove impurities, so antonyms for this word would be words that mean to add or increase impurities, or to not purify. Some antonyms for depurgating are contaminating, polluting, defiling, tainting, corrupting, befouling, soiling, dirtying, sullying, and fouling. These words all suggest the opposite of depurgating, which is to make something pure, clean, or free from impurities. Knowing antonyms for a word can be helpful in understanding its meaning more thoroughly and using it effectively in writing and speech.