The word "destimulate" means to reduce or stop the production of stimulation. Synonyms for this word include "deaden," "calm," "soothe," "sedate," "tranquilize," "relax," "pacify," "compose," "placate," "mollify," "appease," "assuage," "alleviate," and "mitigate." These words imply a calming effect on the person or situation, reducing any agitation or stress. It can be used to describe the action of anesthetics, calming a person's nerves before surgery, or the effect of a peaceful environment in calming one's mind. Ultimately, any of these synonyms describe the same concept, to reduce or eliminate stimulation and bring a sense of peace and calm.