"Dis-regardful" means to be careless or unconcerned about something or someone. The antonym for the word "dis-regardful" is "mindful," meaning to be attentive and conscious of something or someone. Being mindful is the opposite of being disregardful, as it entails being aware and considerate of the feelings, needs, and expectations of others. Other possible antonyms for "dis-regardful" include attentive, observant, heedful, vigilant, and mindful. Using antonyms can help us to express our thoughts and feelings more precisely, and improve our communication skills.