Extenuatives are substances or medications that are used to reduce the severity of a disease or condition, especially by mitigating pain or inflammation. Synonyms for this term includes "alleviators," "soothing agents," "mitigators," and "palliative treatments." Other words that can be used in place of extenuatives include "moderators," "remedies," "analgesics," "antiphlogistic agents," and "anti-inflammatory drugs." Regardless of the synonym used, the ultimate goal of these treatments is to help patients manage their symptoms and improve their quality of life. Whether through medication or other methods, extenuatives will continue to play an essential role in healthcare.