Synonyms for In the first place:

• adv

  •most importantly (adverb)
  • chiefly.
  •Other relevant words: (adverb)
  • start with,
  • on the whole,
  • in first place,
  • before all else,
  • at the outset,
  • to start with,
  • begin with,
  • first off,
  • from the start,
  • in general,
  • in the main,
  • to begin with,
  • predominantly,
  • first and foremost,
  • first.
  •principally (adverb)
  • pre-eminently.

• adv.

  •all (adverb)
  • in the first place,
  • earlier,
  • originally,
  • primarily.
  •chiefly (adverb)
  • mainly,
  • especially,
  • usually,
  • mostly,
  • overall,
  • principally,
  • above all,
  • largely.
  •first (adverb)
  • beforehand.
  •first off (adverb)
  • primo,
  • first thing,
  • foremost,
  • immediately,
  • up front.
  •originally (adverb)
  • formerly,
  • primitively,
  • basically,
  • incipiently,
  • at the start,
  • by birth,
  • by origin.
  •principally (adverb)
  • importantly,
  • supremely,
  • superlatively,
  • materially,
  • before anything else,
  • to a great degree,
  • fundamentally,
  • vitally,
  • peculiarly,
  • for the most part,
  • universally,
  • substantially,
  • eminently,
  • Prevalently,
  • notably,
  • generally,
  • preeminently,
  • dominantly,
  • Prevailingly,
  • particularly,
  • cardinally.

• n.

  •Other relevant words: (noun)
  • firstly,
  • initially.

• Other synonyms:

  •Other relevant words:
  • essentially,
  • in the beginning,
  • at first.
  •Other relevant words (noun):
  • first of all,
  • before everything.

Antonyms for In the first place:

• adv.

  • all
    secondarily.
  • chiefly
    unimportantly.
  • first
    finally, last.
  • principally
    trivially.