Light chain deposition disease (LCDD) is a rare type of disorder that affects the kidneys and other organs in the body. It is caused by the accumulation of abnormal proteins known as light chains in the tissues. LCDD is also known by various synonyms such as light chain cast nephropathy, light chain amyloidosis and monoclonal gammopathy-related kidney disease. These synonyms are used interchangeably to describe the same condition and highlight the different aspects of the disease. Despite the different names, the underlying cause and symptoms of LCDD are similar, and the treatment strategy may vary depending on the severity of the disease. Overall, early detection and prompt treatment can help improve the prognosis of LCDD.