Meriwether Lewis was one of the most famous explorers in American history. He is best known for leading the Lewis and Clark Expedition, which was a pioneering journey from the Mississippi River to the Pacific Ocean. Lewis was an intelligent and fearless explorer who brought back valuable information and specimens from his travels. Some possible synonyms for Meriwether Lewis might include: adventurer, explorer, trailblazer, pioneer, discoverer, or traveler. Each of these words captures a different aspect of Lewis's life and work, whether it be his courage, curiosity, or determination to explore the unknown.