The term "most middlemost" is not commonly used in the English language, and therefore, it is not associated with any direct antonyms. However, if we consider the term in a broader sense, it could be interpreted as referring to the central point or the midpoint. In that case, some of the antonyms could be "extreme," "edge," "periphery," "end," and "corner." These terms describe positions that are farthest or most distant from the central point. If we take "most middlemost" to imply being the most average or typical, some of the antonyms could be "unique," "unconventional," "extraordinary," "exceptional," or "unusual." These synonyms describe something that is not standard or typical.