The antonyms for the word "most woundup" are "relaxed," "calm," "serene," "composed," and "tranquil." When someone is described as the "most woundup," it means they are highly strung, anxious or stressed out. However, the opposite can be used to describe someone who is calm and composed, exhibiting little to no signs of stress or anxiety. Such a person can be referred to as "serene" or "tranquil," evincing an aura of peace and tranquility. Therefore, when you find yourself the "most woundup," try some relaxation techniques such as deep breathing, yoga, or meditation to help you attain a peaceful demeanor.