Non-allergic airway disease refers to conditions that cause difficulty in breathing but are not related to allergens. Synonyms for this term include non-asthmatic bronchitis, chronic obstructive pulmonary disease (COPD), and adult onset asthma. These conditions are often characterized by inflammation of the airways, which can result in coughing, wheezing, and shortness of breath. Common causes of non-allergic airway disease include exposure to cigarette smoke, air pollution, and respiratory infections. Treatment options may include medications to reduce inflammation, breathing exercises, and lifestyle modifications. Early diagnosis and treatment can help manage symptoms and improve overall lung function.