The two-letter word "p is" can be replaced with a variety of synonyms depending on the context. In math and science, "p is" may refer to the constant pi, which is 3.14 (approximately) and is used to calculate the circumference and area of circles. In language, "p is" can be replaced with more descriptive words like "represents," "indicates," or "signifies." Alternatively, it can be substituted with more colloquial terms such as "means" or "stands for." Regardless of the context, it is important to choose the appropriate synonym for "p is" to accurately convey meaning and avoid confusion.