Pyoderma gangrenosum (PG) is a rare skin condition that affects a small percentage of the population. It is characterized by painful and severe ulcers that typically occur on the legs but can also appear on other areas of the body. There are no exact synonyms for the condition, but some words that are often used to describe it include necrotic, ulcerative, and dermatological. Other conditions that may be mistaken for pyoderma gangrenosum include venous ulcers, pressure ulcers, and diabetic ulcers. Treatment typically involves the use of immunosuppressive medications and antibiotics, and early intervention is critical for successful treatment outcomes.