Staphylococcal enterotoxin B (SEB) is a toxic protein produced by the bacterium Staphylococcus aureus. It is a potent stimulator of T-cell activation and can cause food poisoning in humans. However, SEB has many synonyms, including staphylococcal poisoning, staph food poisoning, staphylococcal intoxication, and toxic shock syndrome. These synonyms often describe different specific symptoms and manifestations caused by SEB, such as gastrointestinal symptoms, fever, and organ failure. Knowing these synonyms can help healthcare professionals diagnose and treat SEB infections more effectively, as well as help the public take precautions to prevent staphylococcal infections.