The expression "take it on the chin" means to endure a setback or disappointment without being discouraged or defeated. There are many possible synonyms for this phrase, including "tough it out," "persevere," "hang in there," "stay strong," "keep your head up," and "soldier on." Other similar phrases could include "roll with the punches," "bounce back," "keep fighting," or "weather the storm." All of these expressions convey the idea that life can be difficult and challenging, but that true strength and grit come from staying positive and persistent in the face of adversity.