Thalassaemia Major is a genetic disorder that affects the production of hemoglobin, leading to severe anemia. This disease is also known as Cooley's Anemia, Mediterranean Anemia, and Beta Thalassemia Major. Thalassaemia Major is a life-long chronic condition that requires lifelong medical care and treatment. Symptoms of the disease include fatigue, weakness, and pale skin. There is no cure for Thalassaemia Major, but regular blood transfusions can help manage the symptoms. Additionally, bone marrow transplantation is a potential treatment option for some patients. Thalassaemia Major is a serious condition that requires ongoing medical attention and support.