Tissue biopsy is a medical procedure that involves removing a small piece of tissue from the body for examination and diagnosis. There are several synonyms for this procedure, including needle biopsy, core biopsy, fine-needle aspiration, and excision biopsy. Needle biopsy is a minimally invasive procedure that involves the removal of a small piece of tissue through a needle. Core biopsy involves the removal of a larger piece of tissue using a needle and a special instrument. Fine-needle aspiration is a procedure that uses a thin needle to remove a small sample of tissue for examination. Excision biopsy is a surgical procedure that involves the removal of an entire lump or suspicious area of tissue.