The toll gene family consists of a group of genes that play a vital role in the innate immune response of both vertebrates and invertebrates. These genes encode receptors that recognize pathogenic microorganisms, triggering a signaling cascade that results in the production of antimicrobial peptides, cytokines, and other immune-related molecules. Synonyms for the toll gene family include the toll-like receptor family, TLR family, and the toll pathway. These synonyms are commonly used in the scientific literature and are essential for clarifying the context of research related to this family of genes. Understanding the importance of this gene family and its synonyms can lead to significant insights into the innate immune response and the development of new treatments for infectious diseases.