Anti-TNF compounds are medications that are used to treat autoimmune conditions, such as rheumatoid arthritis, psoriasis, and Crohn's disease. These medications work by blocking a protein called tumor necrosis factor-alpha (TNF-alpha), which plays a role in inflammation. There are several synonyms for the term "anti-TNF compound" that can be used to describe these medications, including TNF inhibitors, TNF blockers, and TNF antagonists. Other related terms include biologic drugs and immunomodulators, which refer more broadly to medications that modify the immune system. Whichever term is used, these powerful medications have revolutionized the treatment of many autoimmune conditions and have helped to improve the quality of life for millions of people around the world.