The phrase "do into" can be substituted with a number of different synonyms depending on context. One alternative is "harm," as in "they did harm to the environment." Another possibility is "damage," as in "the storm did a lot of damage to the crops." "Destroy" is also a suitable substitute, as in "the fire did a lot of damage and destroyed several homes." "Sabotage" is another option, meaning "to intentionally cause harm or damage," as in "it was suspected that someone had sabotaged the machine." Other synonyms include "ruin," "wreck," and "injure." Each of these words conveys a sense of harm or damage caused by some action or event.