Antonyms for the word "freshened up" would include words that describe the opposite of feeling clean, revitalized, or invigorated. These words might include "dirty," "grimy," "lackluster," "dull," "tired," "exhausted," or "drained." Where freshening up is about a renewed sense of energy, cleanliness, and vitality, its opposite would be something altogether lackluster and tired, a lack of energy and vibrancy or a sense of feeling unclean, fatigued, or worn out. Whether through a lack of sleep, poor hygiene, or simply a dull and uneventful existence, the lack of freshening up can lead to a feeling of disconnection from one's surroundings and struggles with energy and motivation.