When it comes to choosing synonyms for the word "girlfriends", there are several options to choose from, depending on the context and tone of the conversation. Some possible options could include "best friends", "sisters", "gal pals", "bffs", "squad", "crew", "tribe", "gal gang", "posse", or simply "friends". Each of these terms offers a slightly different connotation, ranging from casual and fun to more formal and tight-knit. Ultimately, the choice of synonym may depend on the nature of the relationship, as well as the desired tone and style of communication.