The term 'hands one' can be replaced with a variety of antonyms depending on the context of its use. For instance, if it refers to a person who is skilled or proficient in a particular task, some suitable antonyms may include novice, beginner, or amateur. Similarly, if the term refers to someone who is well-versed in a particular subject, some antonyms may include ignorant, uninformed, or uneducated. Other possible antonyms for the word 'hands one' may include clumsy, awkward, untalented, or inept, depending on how it is used. Ultimately, the choice of antonym would depend on the specific word being used and the intended meaning of the phrase.