The phrase "has one nose grindstone" refers to someone who is overly focused on their own concerns, often to the detriment of others. Synonyms for this phrase include self-absorbed, egocentric, self-centered, narcissistic, and selfish. These words all describe someone who is primarily concerned with their own needs and desires, often at the expense of others. Other related synonyms include self-indulgent, self-serving, and self-involved. These words all convey a sense of selfishness or self-importance, and are often used to describe people who are perceived as being insensitive or uncaring towards others.