The word "most abused" can be replaced with several synonyms that convey the same or similar meaning. One alternative is the term "overused," which implies that something has been relied on too heavily or excessively. Another option is "misused," indicating that the item or concept has been used in an incorrect or inappropriate manner. "Exploited" is another possible synonym that suggests something has been taken advantage of or used unfairly for personal gain. Lastly, "maltreated" can be used to convey mistreatment or abuse towards a person or an object. These synonyms help to expand vocabulary and add nuance to communication.