The word "most beleaguered" refers to something or someone who is under siege or experiencing great difficulty. Its antonyms, on the other hand, are words that represent the opposite of this meaning. Some of its antonyms include "flourishing," "prosperous," "successful," and "triumphant." These words imply a state of good fortune, thriving, and success. Other antonyms include "secure," "protected," "comfortable," and "peaceful," which imply a sense of safety, comfort, and stability. It's worth noting that the antonyms of "most beleaguered" are often used to describe people, societies, or situations that are experiencing favorable circumstances.