Antonyms for the word "most high-wrought" are calmer, placid, tranquil, peaceful, serene, quiet, relaxed, and low-key. These antonyms are used to describe things or situations that are less intense and emotional compared to something that is high-wrought. High-wrought implies a level of intensity and tension, which may cause anxiety or discomfort. Calm and tranquil, on the other hand, suggest a sense of relaxation and ease. These words are often used to describe environments, people, or situations that are peaceful and free from any stress, making them the opposite of high-wrought.