The phrase "most man-to-man" can be replaced by several synonyms, including direct, upfront, candid, frank, and honest. These words describe a communication or interaction style that is characterized by clarity, sincerity, and authenticity. "Direct," for example, suggests a straightforward and unambiguous approach, while "upfront" connotes a willingness to be transparent and disclose information without hesitation. "Candid" and "frank" both entail being open and truthful, without sugarcoating or embellishing the details. Overall, these synonyms suggest an unguarded and open style of communication, which can foster trust and build strong relationships between people.