When it comes to describing the accuracy of a shot or a statement, the phrase "most well-aimed" may not always fit the bill. There are plenty of synonyms that can convey the same sense of precision without using the exact same wording. Some alternatives to "most well-aimed" might include "perfectly targeted," "spot on," "bullseye," "dead center," "razor sharp," "pinpoint," "exact," or "precise." Each of these options highlights the idea of hitting a specific target with great proficiency, making them excellent choices for describing everything from a sniper's shot to a particularly effective argument or accusation.