The skin may be regarded as an organ supplementary in its action to the lungs and kidneys, since by its secretion it is capable of removing a considerable quantity of water from the blood; it also removes small quantities of carbon dioxid, salts, and in certain instances during suppression of the renal secretions a small quantity of urea.
"Special Report on Diseases of Cattle"
U.S. Department of Agriculture J.R. Mohler
The result is the production of symptoms more violent than in renal calculi, though not varying, save in intensity, from those of renal colic.
"Special Report on Diseases of Cattle"
U.S. Department of Agriculture J.R. Mohler
Emma's low cardiac output had deteriorated to the point that her left leg below the knee was swollen to almost twice its normal size, owing to renal retention of fluid, and she was so short of breath she required oxygen.
"Syndrome"
Thomas Hoover