Sloughed off is a term commonly used to describe the act of discarding something, removing it or getting rid of it. The opposite of sloughing off can be phrased as to "hold onto," "retain," or "keep". These antonyms imply a sense of holding onto something rather than discarding it or freeing oneself from it. Another antonym for sloughed off is to "embrace" or to "adopt," which implies taking on something rather than discarding it. These opposite meanings of sloughing off can be applicable in various contexts, including emotional, physical, and mental aspects of life.