When it comes to synonyms for the phrase "treat with," there are many different options to choose from. For example, you could use the phrase "deal with" as a replacement, or you could opt for "handle" instead. Other options include "manage," "address," "respond to," or "confront." Each of these phrases can be used in a slightly different context, depending on the situation you are facing. However, they all share the same core meaning of responding to or managing a particular issue or situation. Whether you're writing a report, an essay, or simply trying to communicate more effectively, using synonyms can help ensure that your message comes across clearly and effectively to your audience.