The phrase "wert acquainted with" can be replaced with a variety of antonyms depending on the context of the sentence. To express unfamiliarity with someone or something, antonyms could include "unfamiliar," "ignorant," "unschooled," or "uninformed." If trying to convey a lack of experience or knowledge regarding a particular topic, antonyms could include "inexperienced," "naive," "ignorant," or "clueless." Alternatively, if trying to express a feeling of distance or disconnection, antonyms could include "distant," "removed," "separate," or "untouched." The choice of antonym depends heavily on the specific context and intended meaning of the original phrase.