Auxotrophy refers to the inability of an organism to synthesize certain compounds that are essential for its growth. Synonyms for auxotrophy include nutrient-dependent growth, obligate nutrition, and metabolic dependence. These terms describe the same biological phenomenon where an organism relies on external sources of nutrients to survive and proliferate. While auxotrophy often refers to microbial growth deficiencies, it can also apply to certain genetic disorders in humans that cause specific amino acid or vitamin deficiencies. In these cases, the individual may require specialized dietary supplements or therapies to meet their essential nutrient needs.