There are plenty of synonyms for artistic work, and choosing the right one depends on the context and the type of work in question. Some options include artwork, creation, masterpiece, production, composition, sculpture, painting, drawing, sketch, design, and crafting. Each of these words implies a different type of creativity and output, and they can be used interchangeably depending on the situation. For example, a sculpture can be described as both an artistic work and a masterpiece, while a design may be considered a creative production or composition. Ultimately, the synonym chosen depends on the particular nuances of the work being described.