Familial Periodic Paralyses is a rare genetic disorder that results in temporary muscle weakness or paralysis. Synonyms for this condition include Periodic Paralysis, Paroxysmal Paralysis, Familial Hypokalemic Paralysis, and Thyrotoxic Hypokalemic Periodic Paralysis. These terms all refer to the same condition but with different underlying causes. Familial Periodic Paralyses often affects the muscles of the arms, legs, and torso, causing weakness and atrophy. The condition is usually managed with medications that increase potassium levels in the blood, as well as lifestyle changes such as dietary modifications and exercise. While there is currently no cure for Familial Periodic Paralyses, early diagnosis and proper treatment can greatly improve quality of life for those affected.