"Get the worst of it" is a phrase used to describe the situation where someone has suffered more than their opponent in a conflict or argument. Some of the synonyms to describe this scenario are "lose out," "come off worst," "be beaten," "suffer defeat," "be at a disadvantage," "take a hit," "fall short," and "come up empty-handed." Each of these synonyms implies a degree of defeat or disadvantage, which is the opposite of "winning" or "coming out on top." In many cases, one can use these words interchangeably with "get the worst of it" to convey a sense of disappointment or vulnerability in a given situation.