There are various synonyms that can be used for the expression "most deputed", which refers to something that is highly authorized or entrusted. Some of the potential options for synonyms include "most designated", "most accredited", "most appointed", "most authorized", and "most empowered". Each of these words carries a slightly different connotation but all convey the sense of something that is given a high level of responsibility or recognition. Depending on the context and intended tone of the sentence, any of these alternatives could be used effectively to replace the phrase "most deputed".