Highly active antiretroviral therapy (HAART) refers to a combination of antiretroviral medications used to treat HIV/AIDS. There are various synonyms for HAART, including combination antiretroviral therapy (cART) and highly effective antiretroviral therapy (HEART). Additionally, some healthcare professionals may simply refer to HAART as HIV treatment or antiretroviral therapy (ART). Regardless of the terminology used, HAART is a critical component of managing HIV/AIDS, as it can reduce viral replication and slow the progression of the disease. Patients who receive HAART may experience an improved quality of life and increased life expectancy, making it an essential treatment option for those living with HIV/AIDS.